TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataKd: 1nMAssay Description:The potency of the [125I]RTI-55 for Dopamine transporter siteMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 3.80nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 3.90nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 3.90nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataKd: 4nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 5.10nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 5.60nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataKd: 7.60nMAssay Description:Dissociation constant(KD) of [3H]WIN-35428 at saturation in rat caudate-putamen tissue pre-incubated in buffer at 100 nM (Dopamine transporter)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataKd: 7.60nMAssay Description:Dissociation constant(KD) of [3H]WIN-35428 at saturation in rat caudate-putamen tissue pre-incubated in buffer at 100 nM (Dopamine transporter)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 7.76nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 7.80nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 8.10nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataKd: 8.60nMAssay Description:Binding affinity to a single, sodium-dependent site on the Dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataKd: 9nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 10nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 10nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 11nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 14nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 14nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataKd: 17nMAssay Description:Dissociation constant(KD) of [3H]WIN-35428 at saturation in rat caudate-putamen tissue pre-incubated in buffer (Dopamine transporter)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 20nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 22nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 23nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 25nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDATMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 28nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 31nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 32nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 33nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 34nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 38nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 40nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 48nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 52nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 58nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 65nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 65nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 66nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 70nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDATMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 91nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 98nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 107nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 107nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 112nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 132nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 140nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDATMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 155nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDATMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKd: 200nMAssay Description:Binding affinity to human DAT expressed in HEK293 cells after 60 mins in presence of [3H]imipramine by liquid scintillation countingMore data for this Ligand-Target Pair